4E-BP1 (Phospho-Thr70) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-4E-BP1 (Phospho-Thr70) antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | 4E-BP1 (Phospho-Thr70) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of 4E-BP1 only when phosphorylated at threonine 70. 4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.Pause A., Nature 371:762-767(1994).Gevaert K., Nat. Biotechnol. 21:566-569(2003).Haghighat A., EMBO |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine70 (T-K-T(p)-P-P) derived from Human 4E-BP1. |
| Other Names | [4EBP1; P/OKCL.6; P/OKCL.6; PHAS-I] |
| Gene, Accession # | [4E-BP1], Gene ID: 1978, NCBI: NP_004086.1, UniProt: Q13541 |
| Catalog # | MBS9401044 |
| Price | $200, $255 |
| Order / More Info | 4E-BP1 (Phospho-Thr70) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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