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Antigenic Specificity | Acetyl-Histone H3 (Lys18) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Acetyl-Histone H3 (Lys18) Antibody detects endogenous levels of total Histone H3 protein only when acetylated at lysine18. H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. |
Immunogen | Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H3 around the acetylated site of Lys18. |
Other Names | [H3 histone; HIST1H3A; Histone cluster 1; H3a] |
Gene, Accession # | Gene ID: 8350, NCBI: NP_003520.1, UniProt: P68431 |
Catalog # | MBS8511174 |
Price | $290 |
Order / More Info | Acetyl-Histone H3 (Lys18) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |