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Antigenic Specificity | Smac/Diablo |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Smac/Diablo Antibody detects endogenous levels of Smac/Diablo. Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases. |
Immunogen | Immunogen: A synthesized peptide derived from human Smac/Diablo |
Other Names | [diablo homolog, mitochondrial isoform 4; Diablo homolog, mitochondrial; diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; Smac] |
Gene, Accession # | [Smac], Gene ID: 56616, NCBI: NP_001265231.1, UniProt: Q9NR28 |
Catalog # | MBS4750432 |
Price | $335 |
Order / More Info | Smac/Diablo Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |