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Antigenic Specificity | Phospho-PTPN11-Y580 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well a |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y580 of human PTPN11 Calculated Molecular Weight: 72kDa |
Other Names | [Phospho-PTPN11-Y580: CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3], [PTPN11; PTPN11; CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; PTP2C; SHPTP2; PTP-1D; PTP-2C; SHP-2; Shp2] |
Gene, Accession # | [PTPN11], Gene ID: 5781, NCBI: Q06124.2, UniProt: Q06124 |
Catalog # | MBS128382 |
Price | $235, $350, $525 |
Order / More Info | Phospho-PTPN11-Y580 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |