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Antigenic Specificity | KIR2DS5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KIR2DS5 antibody detects endogenous levels of total KIR2DS5. Function: Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PubMed:28685972, PubMed:18624290, PubMed:18682925). Able to activate NK cells citotoxicity and cytokine production such as IFNG (PubMed:18624290, PubMed:24269691). Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry (PubMed:28685972).Subunit Structure: Interacts with TYROBP.Post-translational Modifications: N-glycosylated, glycosylation varies depending on th |
Immunogen | Immunogen: A synthesized peptide derived from human KIR2DS5 Subcellular Location: Cell Membrane; Single-Pass Type I Membrane Protein Tissue Specificity: Expressed on a discrete subset of peripheral blood NK cells. |
Other Names | [CD158 antigen like family member G; CD158g; Flags: Precursor; Killer cell immunoglobulin like receptor 2DS5; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 5; KIR2DS5; MHC class I NK cell receptor; Natural killer associated transcript 9; Natural killer cell inhibitory receptor; NKAT 9; NKAT9] |
Gene, Accession # | [KIR2DS5], Gene ID: 3810, NCBI: NP_055328.2, UniProt: Q14953 |
Catalog # | MBS9609918 |
Price | $240, $280 |
Order / More Info | KIR2DS5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |