KIR2DS5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKIR2DS5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: KIR2DS5 antibody detects endogenous levels of total KIR2DS5. Function: Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PubMed:28685972, PubMed:18624290, PubMed:18682925). Able to activate NK cells citotoxicity and cytokine production such as IFNG (PubMed:18624290, PubMed:24269691). Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry (PubMed:28685972).Subunit Structure: Interacts with TYROBP.Post-translational Modifications: N-glycosylated, glycosylation varies depending on th
ImmunogenImmunogen: A synthesized peptide derived from human KIR2DS5 Subcellular Location: Cell Membrane; Single-Pass Type I Membrane Protein Tissue Specificity: Expressed on a discrete subset of peripheral blood NK cells.
Other Names[CD158 antigen like family member G; CD158g; Flags: Precursor; Killer cell immunoglobulin like receptor 2DS5; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 5; KIR2DS5; MHC class I NK cell receptor; Natural killer associated transcript 9; Natural killer cell inhibitory receptor; NKAT 9; NKAT9]
Gene, Accession #[KIR2DS5], Gene ID: 3810, NCBI: NP_055328.2, UniProt: Q14953
Catalog #MBS9609918
Price$240, $280
Order / More InfoKIR2DS5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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