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Antigenic Specificity | ENAH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ENAH antibody detects endogenous levels of total ENAH. Function: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity).Subunit Structure: Homotetramer (By similarity). Interacts with APBB1IP, APBB1, PFN1 and ROBO4. Isoforms, containing the polyproline-rich regions with PPLP motifs, bind the WW domain of APBB1IP. Isoforms, containing the PPSY motif, bind, in vitro, to the WW2 and WW3 do |
Immunogen | Immunogen: A synthesized peptide derived from human ENAH Subcellular Location: Cytoplasm. Cytoplasm > Cytoskeleton. Cell Projection > Lamellipodium. Cell Projection > Filopodium. Cell Junction > Synapse. Cell Junction > Focal Adhesion. Targeted to the leading edge of lamellipodia and filopodia by MRL family members. Colocalizes at filopodial tips with a number of other proteins including vinculin and zyxlin. Colocalizes with N-WASP at the leading edge. Colocalizes with GPHN and PFN at synapses. |
Other Names | [ENA; Enah; ENAH_HUMAN; MENA; NDPP1; Protein enabled homolog] |
Gene, Accession # | [ENAH], Gene ID: 55740, NCBI: NP_001008493.1, UniProt: Q8N8S7 |
Catalog # | MBS9608685 |
Price | $240, $280 |
Order / More Info | ENAH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |