Edit |   |
---|---|
Antigenic Specificity | TLR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total TLR1 protein. Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/T |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human TLR1. |
Other Names | [TLR1; CD281; DKFZp547I0610; DKFZp564I0682; KIAA0012] |
Gene, Accession # | [TLR1], Gene ID: 7096, NCBI: NP_003254.2, UniProt: Q15399 |
Catalog # | MBS9402959 |
Price | $255 |
Order / More Info | TLR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |