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Antigenic Specificity | AMPK alpha1 |
Clone | [6B6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | Protein A purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. |
Immunogen | Immunogen: Synthetic Peptide Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 Conjugation: Unconjugated |
Other Names | [PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1] |
Gene, Accession # | [AMPK alpha1], Gene ID: 5562, NCBI: NP_006242.5, UniProt: Q13131 |
Catalog # | MBS2548902 |
Price | $110, $150, $225 |
Order / More Info | AMPK alpha1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |