Human E3 ubiquitin-protein ligase SIAH1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human E3 ubiquitin-protein ligase SIAH1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (ELL2, MYB, POU2AF1, PML and RBBP8), a cell surface receptor (DCC), the cell-surface receptor-type tyrosine kinase FLT3, the cytoplasmic signal transduction molecules (KLF10/TIEG1 an |
| Immunogen | Immunogen: Recombinant human E3 ubiquitin-protein ligase SIAH1 protein(1-313aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5505 / sc-5506 / sc-5504 / sc-22765 |
| Other Names | [Seven in absentia homolog 1; Siah-1; Siah-1a; SIAH1; HUMSIAH], [SIAH1; SIAH1; SIAH1A; HUMSIAH; Siah-1] |
| Gene, Accession # | [SIAH1], Gene ID: 6477, NCBI: NP_001006611.1, UniProt: Q8IUQ4 |
| Catalog # | MBS1496411 |
| Price | $120, $160 |
| Order / More Info | Human E3 ubiquitin-protein ligase SIAH1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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