MCRS1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MCRS1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MCRS1 antibody detects endogenous levels of total MCRS1. Function: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).Subunit Structure: Component of the chromatin remodeling INO80 compl |
| Immunogen | Immunogen: A synthesized peptide derived from human MCRS1 Subcellular Location: Nucleus. Nucleus > Nucleolus. In microspherules in the nucleolus. Tissue Specificity: Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (80%), Bovine (100%), Horse (100%), Sheep (100%), Rabb |
| Other Names | [58 kDa microspherule protein; Cell cycle regulated factor (78 kDa); Cell cycle regulated factor p78; Cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; MCRS 1; MCRS 2; MCRS1; MCRS1_HUMAN; MCRS2; Microspherule protein 1; MSP 58; MSP58; p78] |
| Gene, Accession # | [MCRS1], Gene ID: 10445, NCBI: NP_001012300.1, UniProt: Q96EZ8 |
| Catalog # | MBS9608738 |
| Price | $240, $280 |
| Order / More Info | MCRS1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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