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Antigenic Specificity | Cadherin-Catenin Antibody Sampler Kit |
Clone | n/a |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 1 kit |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Adherens junctions are dynamic structures that form cell-cell contacts and are important in development, differentiation, tissue integrity, morphology and cell polarity. They are composed of cadherins that are transmembrane proteins that bind cadherins on adjacent cells in a calcium dependent manner. On the cytoplasmic side of adherens junctions, the cadherins associate with beta-catenin, gamma-catenin and p120 catenin (delta). beta- catenin and gamma-catenin associate with alpha-catenin, which links the cadherincatenin complex to the actin cytoskeleton. Recent studies indicate that cancer cells exhibit increased N-cadherin and diminished E-cadherin expression. E-cadherin is considered a suppressor of invasive cancer cell growth |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS2550008 |
Price | $345 |
Order / More Info | Cadherin-Catenin Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |