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Antigenic Specificity | CD40LG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD40LG antibody detects endogenous levels of total CD40LG. Description: CD40 Ligand (CD40L), a member of the TNF superfamily of ligands, is expressed as either a membrane-bound or soluble homotrimer (1). Both membrane-bound and soluble forms of CD40L have biological activity (1, 2). CD40L is expressed primarily on activated T cells; however, mast cells, basophils, and NK cells may also express CD40L (1). CD40L functions as an important T cell co-stimulatory molecule and enhances T-dependent B cell responses (1, 2). CD40L binds CD40, which is a receptor expressed on B cells, dendritic cells, and macrophages (1). Binding of CD40L to CD40 leads to the recruitment of TRAF proteins (TRAFs 2, 3, 5, and 6) resulting in the activation |
Immunogen | Immunogen: N term-peptide of human CD40LG Subcellular Location: Secreted and Cell Membrane. Tissue Specificity: Specifically expressed on activated CD4 T-lymphocytes. |
Other Names | [CD 40L; CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand, soluble form; CD40-L; CD40L; CD40L_HUMAN; CD40LG; gp39; hCD40L; HIGM1; IGM; IMD3; T B cell activating molecule; T BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TrAP; Tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5] |
Gene, Accession # | [CD40LG], Gene ID: 959, NCBI: NP_000065.1, UniProt: P29965 |
Catalog # | MBS9606758 |
Price | $240, $280 |
Order / More Info | CD40LG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |