c-Myc Oncoprotein Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-Myc Oncoprotein
Clone[MYC275 + MYC909]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCLs) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differentia
ImmunogenImmunogen: Recombinant human c-myc protein
Other Names[Class E basic helix-loop-helix protein 39 (bHLHe39), MRTL, Myc2, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, V-Myc avian myelocytomatosis viral oncogene homolog], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39]
Gene, Accession #[MYC], Gene ID: 4609, NCBI: NP_002458.2, UniProt: P01106
Catalog #MBS439219
Price$190, $340, $340
Order / More Infoc-Myc Oncoprotein Antibody from MYBIOSOURCE INC.
Product Specific ReferencesEvan GI, et. al. Molecular and Cellular Biology, 1985, 5(12):3610-6
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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