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Antigenic Specificity | c-Myc Oncoprotein |
Clone | [MYC275 + MYC909] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCLs) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differentia |
Immunogen | Immunogen: Recombinant human c-myc protein |
Other Names | [Class E basic helix-loop-helix protein 39 (bHLHe39), MRTL, Myc2, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, V-Myc avian myelocytomatosis viral oncogene homolog], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39] |
Gene, Accession # | [MYC], Gene ID: 4609, NCBI: NP_002458.2, UniProt: P01106 |
Catalog # | MBS439219 |
Price | $190, $340, $340 |
Order / More Info | c-Myc Oncoprotein Antibody from MYBIOSOURCE INC. |
Product Specific References | Evan GI, et. al. Molecular and Cellular Biology, 1985, 5(12):3610-6 |