CD31 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD31
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionCD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells and endothelial cells, and modulates cell adhesion, endothelial cell migration and angiogenesis (1). CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical stress or oxidative stress), presumably by Src family members (2). The tyrosine phosphorylation mediates associations with a number of SH2 domain containing binding partners such as PI3-kinase, SHIP, PLCgamma and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules (3).
ImmunogenImmunogen: A synthetic peptide of human CD31 Calculated Molecular Weight: 83kDa
Other Names[PECAM1; CD31; FLJ58394; PECAM-1], [PECAM1; PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; PECAM-1]
Gene, Accession #[PECAM1], Gene ID: 5175, NCBI: P16284.1, UniProt: P16284
Catalog #MBS126974
Price$200, $275, $430
Order / More InfoCD31 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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