Edit |   |
---|---|
Antigenic Specificity | MIA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MIA2 antibody detects endogenous levels of total MIA2. Function: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed:27138255). Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity).Subunit Structure: Isoform 1 may interact with APOB and MIA3 (PubMed:27138255). Isoform 1 may interact with the COPII coat subunits SEC23A and SEC24C (By similarity).Similarity: The proline |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Secreted. Tissue Specificity: Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis (PubMed:12586826). Isoform 1 is specifically expressed in lung, testis, small intestine, colon, pancreas, kidney, liver and prostate (PubMed:27138255). |
Other Names | [FLJ22404; Melanoma inhibitory activity 2; Melanoma inhibitory activity protein 2; Mia2; MIA2_HUMAN] |
Gene, Accession # | [MIA2], Gene ID: 4253, NCBI: NP_001316143.1, UniProt: Q96PC5 |
Catalog # | MBS9605611 |
Price | $240, $280 |
Order / More Info | MIA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |