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Antigenic Specificity | Tau (pS202) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes phosphorylated Serine 202 of human Tau protein. It does not recognize the non-phosphorylated Tau or other phosphorylation sites. Tau is a microtubule-associated phosphoprotein (MAP), localized in neuronal axons. It promotes tubulin polymerization and stabilizes microtubules. Tau proteins constitute a family of six isoforms which range from 352 to 441 amino acids. The tau variants differ from each other by the presence of either three or four repeat-regions in the carboxy-terminal part of the molecule and the absence or presence of one or two inserts in the amino-terminal part. Tau is hyperphosphorylated by ERK, GSK-3, TPKII and CDK5, at least thirty phosphorylation sites have been described, including Thr39, Ser46, |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [Tau], Gene ID: 4137 |
Catalog # | MBS460526 |
Price | $285 |
Order / More Info | Tau (pS202) Antibody from MYBIOSOURCE INC. |
Product Specific References | M.Goedert, et al. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases. FEBS Letters, 409 (1), 57-62 (2009). |