FKRP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFKRP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: FKRP antibody detects endogenous levels of FKRP. Description: FKRP Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1). Belongs to the licD transferase family. May interact with the dystrophin-glycoprotein complex (DGC).Function: Transferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.Subunit Structure: May interact with the dystrophin-glycoprotein complex (DGC) (By similarity). Homodimer; disulfi
ImmunogenImmunogen: A synthesized peptide derived from human FKRP Subcellular Location: Golgi Apparatus. Secreted. Cell Membrane > Sarcolemma. Rough Endoplasmic Reticulum. According to some studies the N-terminal hydrophobic domain is cleaved after translocation to the Golgi apparatus and the protein is secreted. According to others the N-terminal hydrophobic domain is a transmembrane domain and the protein is a type II transmembrane type targeted to the Golgi apparatus by a non-cleavable signal anchor s
Other Names[Fkrp; FKRP_HUMAN; FLJ12576; Fukutin related protein; Fukutin-related protein; LGMD2I; MDC1C; MGC2991]
Gene, Accession #[FKRP], Gene ID: 79147, NCBI: NP_001034974.1, UniProt: Q9H9S5
Catalog #MBS9600396
Price$240, $280
Order / More InfoFKRP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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