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Antigenic Specificity | LTA |
Clone | [AT15A3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lymphotoxin-alpha (LT-alpha; LTA) is member of the TNF ligand superfamily, bind the same TNF receptor and mediate similar pleiotropic effect. LTA, located within the MHC III region of chromosome 6, show close linkage to the HLA class I (HLA-B) and class II (HLA-DR) genes. LTA is proinflammatory cytokine with important biological activity and immunomodulatory function and be known to influence a variety of cellular response. In particular, Polymorphism in the gene encoding LTA appears to contribute to infectious disease susceptibility and infection. |
Immunogen | Immunogen: Recombinant human LTA (35-205aa) purified from E.coli |
Other Names | [Lymphotoxin alpha, CLTalpha, Coley's toxin, DIF, Differentiation inducing factor, Hemorrhagic factor, LT, LT alpha, LTA, LTalpha, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), Natural killer cytotoxic factor, Necrosin, NKCF, OTTHuMP00000037612, OTTHuMP00000037613, TNF B, TNF superfamily member 1, TNFB, TNFbeta, TNFSF 1, TNFSF1, Tumor necrosis factor beta, Tumor necrosis factor ligand superfamily member 1, Tumor necrosis factor superfamily member 1, Lymphotoxin alpha], [LTA; LTA; LT; TNFB; TNFSF1; TNLG1E; TNFB; TNFSF1; LT-alpha] |
Gene, Accession # | [LTA], Gene ID: 4049, NCBI: NP_001153212, UniProt: P01374 |
Catalog # | MBS200189 |
Price | $240, $315 |
Order / More Info | LTA Antibody from MYBIOSOURCE INC. |
Product Specific References | Ovsyannikova IG, et al. (2010) PLoS One, 5 (7):e11806; Boraska V, et al. (2010) BMC Med Genet, 11-69.; Sala A, et al. (2010) Pharmacol Rep, 62 (3):503-10. |