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Antigenic Specificity | Mouse IL-6 |
Clone | [MAB0847] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) - Formalin, Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of IL-6. |
Other Names | [Il6; Il-6], [Il6; Il6; Il-6; Il-6; IL-6] |
Gene, Accession # | [IL-6], Gene ID: 16193, NCBI: NP_112445.1, UniProt: P08505 |
Catalog # | MBS690344 |
Price | $490 |
Order / More Info | Mouse IL-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |