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Antigenic Specificity | Human Transcriptional enhancer factor TEF-5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.This gene pro |
Immunogen | Immunogen: Recombinant human Transcriptional enhancer factor TEF-5 protein |
Other Names | [DTEF-1; TEA domain family member 3; TEAD-3; TEAD3; TEAD5; TEF5] |
Gene, Accession # | Gene ID: 7005, NCBI: NP_003205.2, UniProt: Q99594 |
Catalog # | MBS7001909 |
Price | $160, $235 |
Order / More Info | Human Transcriptional enhancer factor TEF-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |