Human Presenilin-2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Presenilin-2 |
| Clone | [7F8] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Vertebrates have two presenilin genes, called PSEN1 (located on chromosome 14 in humans) that encodes presenilin 1 (PS-1) and PSEN2 (on chromosome 1 in humans) that codes for presenilin 2 (PS-2). Both genes show conservation between species, with little difference between rat and human presenilins. The nematode worm C. elegans has two genes that resemble the presenilins and appear to be functionally similar, sel-12 and hop-1. Presenilins undergo cleavage in an alpha helical region of one of the cytoplasmic loops to produce a larger N-terminal and a smaller C-terminal fragment that together form part of the functional protein. Cleavage of presenilin 1 can be prevented by a mutation that causes the loss of exon 9, and results in loss of funct |
| Immunogen | Preparation: This antibody was produced from a hybridoma (mouse myeloma fused wuth spleen cells from mouse) immunized with recombinant human Presenilin-2. Antigen: Recombinant human Presenilin-2. Reconstitution Buffer: PBS sterile). |
| Other Names | [PSEN2; AD4; PS2; AD3L; STM2; CMD1V], [PSEN2; PSEN2; AD4; PS2; AD3L; STM2; CMD1V; AD4; PS2; PSNL2; STM2; PS-2] |
| Gene, Accession # | Gene ID: 5664, NCBI: NP_000438.2, UniProt: P49810 |
| Catalog # | MBS690158 |
| Price | $490 |
| Order / More Info | Human Presenilin-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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