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Antigenic Specificity | BETA AMYLOID (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects beta amyloid, an 87kDa member of the amyloid precursor protein family expressed in the adult brain. Beta amyloid is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer's disease (AD). Multiple transcript variants encoding several different isoforms have been found for this gene.. . Mutations to the gene can also cause cerebroarterial amyloidosis (cerebral amyloid angiopathy). MBS222343 detects beta amyloid, an 87kDa mem |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acid sequence 1-14 of human Amyloid Beta protein. Histology Positive Control Tissue: Human Alzheimer disease brain. Antiserum Preparation: Antisera to amyloid beta (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Target Species: Human |
Other Names | [amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; alzheimer disease amyloid protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II; amyloid beta (A4) precursor protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II], [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)] |
Gene, Accession # | Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067 |
Catalog # | MBS222343 |
Price | $375 |
Order / More Info | BETA AMYLOID (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |