CADM1 (N-term), 66-94 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CADM1 (N-term), 66-94 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CADM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CADM1. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote co |
| Immunogen | n/a |
| Other Names | [Cell adhesion molecule 1; Immunoglobulin superfamily member 4; IgSF4; Nectin-like protein 2; NECL-2; Spermatogenic immunoglobulin superfamily; SgIgSF; Synaptic cell adhesion molecule; SynCAM; Tumor suppressor in lung cancer 1; TSLC-1; CADM1 HGNC:5951)] |
| Gene, Accession # | [CADM1], Gene ID: 23705, NCBI: NP_001091987.1, UniProt: Q9BY67 |
| Catalog # | MBS9205898 |
| Price | $165, $370 |
| Order / More Info | CADM1 (N-term), 66-94 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) McGovern, D.P., et al. Hum. Mol. Genet. 19(17):3468-3476(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : You, Y., et al. Melanoma Res. 20(3):179-183(2010) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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