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Antigenic Specificity | BCL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed: 17418785). |
Immunogen | Immunogen: Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA) |
Other Names | [Apoptosis regulator Bcl-2; BCL2] |
Gene, Accession # | [BCL2], Gene ID: 596, NCBI: NP_000624.2, UniProt: P10415 |
Catalog # | MBS7049607 |
Price | $160, $235 |
Order / More Info | BCL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |