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Antigenic Specificity | BRMS-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein. BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein (breast cancer metastasis suppressor 1) encoded by BRMS1 localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human BRMS-1 at AA range: 40-120 |
Other Names | [Rabbit BRMS-1; BRMS1; Breast cancer metastasis-suppressor 1] |
Gene, Accession # | [BRMS-1], Gene ID: 25855, NCBI: NP_056214.1, UniProt: Q9HCU9 |
Catalog # | MBS9701521 |
Price | $130, $220, $325 |
Order / More Info | BRMS-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |