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Antigenic Specificity | TNFRSF14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-κB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potentia |
Immunogen | Immunogen: TNFRSF14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TNFRSF14. Buffer: TNFRSF14 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; UNQ329/PRO509; Tumor necrosis factor receptor superfamily member 14; Herpes virus entry mediator A; Herpesvirus entry mediator A; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)], [TNFRSF14; TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; HVEA; HVEM; Herpesvirus entry mediator A; HveA; TR2] |
Gene, Accession # | [TNFRSF14], Gene ID: 8764, NCBI: Q92956.3, UniProt: Q92956 |
Catalog # | MBS150920 |
Price | $375 |
Order / More Info | TNFRSF14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |