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Antigenic Specificity | LIPA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human acid lipase/cholesteryl esterase (LIPA) is a 46-kDa glycoprotein required for the lysosomalhydrolysis of cholesteryl esters and triglycerides that cells acquire through the receptor-mediatedendocytosis of low-density lipoproteins(PMID8432549). Defects in LIPA are the cause ofWolman disease (WOD)(PMID:8146180) and cholesteryl ester storage disease (CESD)(PMID:9633819). It has 2 isoforms produced by alternative splicing with the molecular weight of45 kDa and 39 kDa. The full length protein has a signal peptide and several glycosylation sites. |
Immunogen | Immunogen: Fusion protein of LIPA Calculated MW: 399aa,45kd Observed MW: 45kd |
Other Names | [CESD, Cholesteryl esterase, LAL, LIPA, Lipase A, Sterol esterase.] |
Gene, Accession # | [LIPA], UniProt: P38571 |
Catalog # | MBS2527039 |
Price | $195, $270, $435 |
Order / More Info | LIPA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |