CD14 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CD14 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD14 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cluster of differentiation 14, CD14 is a pattern recognition receptor that plays a central role in innate immunity through recognition of bacterial lipopolysaccharide, primarily LPS.1 CD14 is a myelomonocytic differentiation antigen expressed by monocytes, macrophages, and activated granulocytes, it is included in the critical region that is frequently deleted in certain myeloid leukemias.2 CD14 has a dual role in nucleic acid-mediated Toll-like receptor (TLR) activation by promoting selective uptake of nucleic acids and acting as a coreceptor for endosomal TLR activation.3 |
| Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of CD14. |
| Other Names | [CD14], [CD14; CD14] |
| Gene, Accession # | [CD14], Gene ID: 281048, NCBI: BAA21517.1, UniProt: Q95122 |
| Catalog # | MBS355169 |
| Price | $275 |
| Order / More Info | CD14 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. LeVan, T. D., Bloom, J. W., Bailey, T. J., Karp, C. L., Halonen, M., Martinez, F. D., Vercelli, D. A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity. J. Immun. 167: 5838-5844, 2001. 2. Goyert, S. M., Ferrero, E., Rettig, W. J., Yenamandra, A. K., Obata, F., Le Beau, M. M. The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors. Science 239: 497-500, 1988. 3. Baumann, C. L., Aspalter, I. M., Sharif, O., Pichlmair, A., Bluml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, K. L., Colinge, J., Knapp, S., Superti-Furga, G. CD14 is a coreceptor of Toll-like receptors 7 and 9. J. Exp. Med. 207: 2689-2701, 2010. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies