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Antigenic Specificity | AKT1S1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against AKT1S1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K)-AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM]. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AKT1S1 |
Other Names | [proline-rich AKT1 substrate 1 isoform a; Proline-rich AKT1 substrate 1; proline-rich AKT1 substrate 1; AKT1 substrate 1; 40 kDa proline-rich AKT substrate] |
Gene, Accession # | [AKT1S1], Gene ID: 84335, NCBI: NP_115751, UniProt: Q96B36 |
Catalog # | MBS3208839 |
Price | $335 |
Order / More Info | AKT1S1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |