Edit |   |
---|---|
Antigenic Specificity | MAP4K3 |
Clone | [219CT8.3.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM,k |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAP4K3 monoclonal antibody is generated from mouse immunized with MAP4K3 recombinant protein. This gene encodes a member of the Ste20 family ofserine/threonine protein kinases. The protein belongs to thesubfamily that consists of members, such as germinal center kinase(GCK), that are characterized by an N-terminal catalytic domain andC-terminal regulatory domain. The kinase activity of the encodedprotein can be stimulated by UV radiation and tumor necrosisfactor-alpha. The protein specifically activates the c-JunN-terminal kinase (JNK) signaling pathway. Evidence suggests thatit functions upstream of mitogen-activated protein kinase kinasekinase 1 (MEKK1). This gene previously was referred to asR |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3; MAP4K3; RAB8IPL1] |
Gene, Accession # | [MAP4K3], Gene ID: 8491, NCBI: NP_001257354.1, UniProt: Q8IVH8 |
Catalog # | MBS9200084 |
Price | $165, $370 |
Order / More Info | MAP4K3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Yan, L., et al. Mol. Cell 37(5):633-642(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) |