MAP4K3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP4K3
Clone[219CT8.3.1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgM,k
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis MAP4K3 monoclonal antibody is generated from mouse immunized with MAP4K3 recombinant protein. This gene encodes a member of the Ste20 family ofserine/threonine protein kinases. The protein belongs to thesubfamily that consists of members, such as germinal center kinase(GCK), that are characterized by an N-terminal catalytic domain andC-terminal regulatory domain. The kinase activity of the encodedprotein can be stimulated by UV radiation and tumor necrosisfactor-alpha. The protein specifically activates the c-JunN-terminal kinase (JNK) signaling pathway. Evidence suggests thatit functions upstream of mitogen-activated protein kinase kinasekinase 1 (MEKK1). This gene previously was referred to asR
Immunogenn/a
Other Names[Mitogen-activated protein kinase kinase kinase kinase 3; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3; MAP4K3; RAB8IPL1]
Gene, Accession #[MAP4K3], Gene ID: 8491, NCBI: NP_001257354.1, UniProt: Q8IVH8
Catalog #MBS9200084
Price$165, $370
Order / More InfoMAP4K3 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Yan, L., et al. Mol. Cell 37(5):633-642(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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