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Antigenic Specificity | CRLF2/Tslp R Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Cytokine receptor-like factor 2 is a protein that in humans is encoded by the CRLF2 gene. This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variant |
Immunogen | Immunogen: E Coli-derived human CRLF2 recombinant protein (Position: A26-K231). Subcellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells. |
Other Names | [Cytokine receptor-like factor 2; Cytokine receptor-like 2; IL-XR; Thymic stromal lymphopoietin protein receptor; TSLP receptor; CRLF2; CRL2; ILXR; TSLPR] |
Gene, Accession # | [CRLF2/Tslp R], Gene ID: 64109, NCBI: NP_001012288.2, UniProt: Q9HC73 |
Catalog # | MBS1750865 |
Price | $280 |
Order / More Info | CRLF2/Tslp R Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |