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Antigenic Specificity | EPC1 (Center), 305-334 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.28 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human EPC1. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, a |
Immunogen | n/a |
Other Names | [Enhancer of polycomb homolog 1; EPC1] |
Gene, Accession # | [EPC1], Gene ID: 80314, NCBI: NP_001258933.1, UniProt: Q9H2F5 |
Catalog # | MBS9213118 |
Price | $165, $370 |
Order / More Info | EPC1 (Center), 305-334 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shimono Y., et al. J. Biol. Chem. 275:39411-39419(2000). Nunes D.N., et al. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. Ota T., et al. Nat. Genet. 36:40-45(2004). Deloukas P., et al. Nature 429:375-381(2004). Mural R.J., et al. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |