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Antigenic Specificity | PREX2 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, mouse, porcine, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against PREX2. It was validated on Western BlotTarget Description: PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PREX2 |
Other Names | [TPA_exp: PtdIns(3,4,5)-dependent Rac exchanger 2a; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; DEP domain-containing protein 2] |
Gene, Accession # | [PREX2], Gene ID: 80243, NCBI: DAA05334.1, UniProt: Q70Z35 |
Catalog # | MBS3218880 |
Price | $365 |
Order / More Info | PREX2 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |