SMURF1 (N-term), 66-96 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SMURF1 (N-term), 66-96 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: Xenopus, zebrafish) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SMURF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human SMURF1. Members of the transforming growth factor-beta (TGFB) family signal through type I and type II serine/threonine-kinase receptors, which in turn activate the SMAD signaling pathway. Bone morphogenetic protein (BMP) receptors target SMAD1, SMAD5, and SMAD8, whereas receptors for activin and TGFB (e.g., ACVR1 and TGFBR1, respectively) target SMAD2 and SMAD3. Phosphorylation of these receptor-regulated SMADs induces their association with the common-partner SMAD, SMAD4. Smurf1, a HECT domain E3 ubiquitin ligase, regulates cell polarity and protrusive activity and is required to ma |
| Immunogen | n/a |
| Other Names | [E3 ubiquitin-protein ligase SMURF1; hSMURF1; 632-; SMAD ubiquitination regulatory factor 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMURF1; KIAA1625] |
| Gene, Accession # | [SMURF1], Gene ID: 57154, NCBI: NP_001186776.1, UniProt: Q9HCE7 |
| Catalog # | MBS9202627 |
| Price | $165, $370 |
| Order / More Info | SMURF1 (N-term), 66-96 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Tajima, Y., et al., J. Biol. Chem. 278(12):10716-10721 (2003). Suzuki, C., et al., J. Biol. Chem. 277(42):39919-39925 (2002). Ebisawa, T., et al., J. Biol. Chem. 276(16):12477-12480 (2001). Zhu, H., et al., Nature 400(6745):687-693 (1999). Lambris, J., et al., J. Immunol. Methods 27(1):55-59 (1979). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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