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Antigenic Specificity | Human CD11b |
Clone | [ICRF44] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD11b is a 165-170 kD type I transmembrane glycoprotein also known as alphaMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin beta2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X. |
Immunogen | n/a |
Other Names | [Integrin alpha-M; Itgam; CD11 antigen-like family member B; CR-3 alpha chain; Leukocyte adhesion receptor MO1; CD11b] |
Gene, Accession # | [CD11b], Gene ID: 3684, NCBI: NP_001139280.1, UniProt: P11215 |
Catalog # | MBS2559075 |
Price | $70, $85, $110 |
Order / More Info | Human CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |