HDAC4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHDAC4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentration1ug/ul
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: HDAC4 (Ab-632) antibody detects endogenous levels of total HDAC4 protein. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. This gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
ImmunogenImmunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human HDAC4 around the phosphorylation site of serine 632 (A-Q-SP-S-P).
Other Names[hdac4; Histone deacetylase], [hdac4]
Gene, Accession #[HDAC4], NCBI: AHN52085.1
Catalog #MBS417191
Price$405
Order / More InfoHDAC4 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWang AH, et al. (2000) Mol Cell Biol. 20(18): 6904-6912.Grozinger CM, et al. (2000) Proc Natl Acad Sci U S A. 97(14): 7835-7840.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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