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Antigenic Specificity | BEST3 (N-term), 40-68 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3. BEST3 belongs to the bestrophin family of anion channels,which includes BEST1 (MIM 607854), the gene mutant in vitelliformmacular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes,BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins aretransmembrane (TM) proteins that share a homology region containinga high content of aromatic residues, including an invariantarg-phe-pro (RFP) motif. The bestrophin genes share a conservedgene structure, with almost identical sizes of the 8 RFP-TMdomain-encoding exons and highly conserved exon-intron boun |
Immunogen | n/a |
Other Names | [Bestrophin-3; Vitelliform macular dystrophy 2-like protein 3; BEST3; VMD2L3] |
Gene, Accession # | [BEST3], Gene ID: 144453, NCBI: NP_116124.2, UniProt: Q8N1M1 |
Catalog # | MBS9213209 |
Price | $165, $370 |
Order / More Info | BEST3 (N-term), 40-68 Antibody from MYBIOSOURCE INC. |
Product Specific References | Marsey, L.L., et al. J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009) : Qu, Z.Q., et al. J. Biol. Chem. 282(24):17460-17467(2007) Tsunenari, T., et al. J. Biol. Chem. 278(42):41114-41125(2003) Stohr, H., et al. Eur. J. Hum. Genet. 10(4):281-284(2002) Marquardt, A., et al. Hum. Mol. Genet. 7(9):1517-1525(1998) |