PIASy (N-term), 48-79 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIASy (N-term), 48-79
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis PIASy antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-79 amino acids from the N-terminal region of human PIASy. PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation.
Immunogenn/a
Other Names[E3 SUMO-protein ligase PIAS4; 632-; PIASy; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma; PIAS-gamma; PIAS4; PIASG]
Gene, Accession #[PIAS4], Gene ID: 51588, NCBI: NP_056981.2, UniProt: Q8N2W9
Catalog #MBS9208040
Price$165, $370
Order / More InfoPIASy (N-term), 48-79 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesImoto, S., et al., J. Biol. Chem. 278(36):34253-34258 (2003). Chun, T.H., et al., Circ. Res. 92(11):1201-1208 (2003). Subramanian, L., et al., J. Biol. Chem. 278(11):9134-9141 (2003). Liu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 98(6):3203-3207 (2001). Liu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 95(18):10626-10631 (1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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