FBXL3 (Phospho-Ser320) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFBXL3 (Phospho-Ser320)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of FBXL3 only when phosphorylated at serine 320. Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3.
Other Names[FBL3A; FBXL3A]
Gene, Accession #[FBXL3], Gene ID: 26224, NCBI: NP_036290.1, UniProt: Q9UKT7
Catalog #MBS9405723
Price$200, $255
Order / More InfoFBXL3 (Phospho-Ser320) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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