Human CD47 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD47 |
| Clone | [8H7] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1,k |
| Format | Protein G purified |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Blocking (BL) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reactive with recombinant and native human CD47. CD47 is a ubiquitously expressed 50 kDa transmembrane protein with an extracellular N-terminal IgV domain. CD47 inhibits phagocytosis through interaction with signal regulatory protein a (SIRPa) on macrophages and other phagocytic cells. Normal cells, especially cells in brain tissue, placenta, prostate, bladder and fallopian tube, expressed abundant CD47. Aged erythrocytes and spontaneous apoptotic cells express less CD47 and are more likely been phagocytized. CD47 expression in many cancer cells are elevated. It is believed that CD47 is a self marker that helps cancer cells to escape from immunity. CD47 is also a receptor for thrombospondin-1 (TSP-1) and integrin. It may play a role in an |
| Immunogen | Immunogen: Human cell expressed recombinant Human CD47 (Gln19-Pro139) with a poly-histidine tag at the C-terminus. Accession #: Q08722. Light Chain: Kappa. Fusion Myeloma: Sp2/0-Ag14. Target Protein: Human CD47 |
| Other Names | [mAb Human CD47; Mouse to human CD47, Clone 8H7; Mouse (mAb) to human CD47], [CD47; CD47; IAP; OA3; MER6; MER6; IAP] |
| Gene, Accession # | [CD47], Gene ID: 961, NCBI: CEJ95640.1 |
| Catalog # | MBS590087 |
| Price | $490 |
| Order / More Info | Human CD47 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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