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Antigenic Specificity | Human HEAT SHOCK PROTEIN 90 ALPHA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chicken (expected from sequence), Drosophila (expected from sequence), monkey (expected from sequence), mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects human heat shock protein 90 alpha (HSP90a), one of two HSP90 isoforms together with HSP90b. These isoforms are encoded by different genes and under normal conditions assist the folding of newly synthesised proteins, and are also important in cellular processes such as hormone signalling and cell cycle control. . . In response to mutation or environmental stress, HSP90 expression is upregulated as part of the heat shock response, and function to maintain newly destabilised proteins in a folding competent state. HSP90 can also affect the epigenetic state at specific loci, leading to phenotype modulation.. . Induction of HSP90a by c-Myc may control the activity of multiple signal pathways involved in cellular transformati |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 289-300 of human heat shock protein 90 alpha. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human heat shock protein 90 alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [heat shock protein HSP 90-alpha isoform 1; Heat shock protein HSP 90-alpha; heat shock protein HSP 90-alpha; HSP 86; LPS-associated protein 2; epididymis luminal secretory protein 52; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; lipopolysaccharide-associated protein 2; renal carcinoma antigen NY-REN-38; heat shock protein 90kDa alpha (cytosolic), class A member 1; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38], [HSP90AA1; HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2] |
Gene, Accession # | Gene ID: 3320, NCBI: NP_001017963.2, UniProt: P07900 |
Catalog # | MBS222823 |
Price | $375 |
Order / More Info | Human HEAT SHOCK PROTEIN 90 ALPHA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |