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Antigenic Specificity | BCL-6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFkappaB expression, thereby inhibiting NFkappaB-mediated cellular functions.HDAC-and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). |
Immunogen | Immunogen: A synthesized peptide derived from human Bcl6 |
Other Names | [B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51; BCL6; BCL5; LAZ3; ZBTB27; ZNF51] |
Gene, Accession # | [BCL-6], Gene ID: 604, NCBI: NP_001124317.1, UniProt: P41182 |
Catalog # | MBS8542277 |
Price | $280 |
Order / More Info | BCL-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |