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Antigenic Specificity | Human Clusterin |
Clone | [P1A11AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: Clusterin also named Apolipoprotein J (APO-J) is a 75-80 kD disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. The precursor polypeptide chain is cleaved proteolytically to remove the 22-mer secretory signal peptide and subsequently between residues 227/228 to generate the ? and ? chains. These are assembled in anti-parallel to give a heterodimeric molecule in which the cysteine-rich centers are linked by five disulfide bridges and are flanked by two predicted coiled-coil ? -helices and three predicted amphipathic a-helices. Across a broad range of species clusterin shows a high degree of sequence homolo |
Immunogen | Immunogen: Anti-human Clusterin mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human Clusterin amino acids 1-333 purified from E Coli. |
Other Names | [Clusterin; Clusterin, Mouse Human; CLI; AAG4; KUB1; SGP2; SGP-2; SP-40; TRPM2; MGC24903; Complement-associated protein SP-40; 40; Complement cytolysis inhibitor; NA1/NA2; Apolipoprotein J; Apo-J; Testosterone-repressed prostate message 2; TRPM-2; Clusterin], [Clu; Clu; CLI; DAG; APOJ; SGP2; SP40; SGP-2; SP-40; Trpm2; Trpmb; TRPM-2; TRPM2B; RATTRPM2B; DAG; SGP-2; TRPM-2] |
Gene, Accession # | Gene ID: 24854, NCBI: NP_444180.2 |
Catalog # | MBS140166 |
Price | $140, $205, $505 |
Order / More Info | Human Clusterin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |