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Antigenic Specificity | M3K13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: M3K13 antibody detects endogenous levels of total M3K13. Description: LZK a TKL kinase of the MLK family. Synergizes with antioxidant protein-1 to activate NF-kappaB. Forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway. This kinase can phosphorylate and activate JNK and MKK7.Function: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.Subunit Structure: Homodimer; forms dimers through the |
Immunogen | Immunogen: A synthesized peptide derived from human M3K13 Subcellular Location: Cytoplasm. Membrane. Tissue Specificity: Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (91%) |
Other Names | [EC 2.7.11.25; Leucine zipper bearing kinase; Leucine zipper-bearing kinase; LZK; M3K13_HUMAN; MAP3K13; MEKK13; MGC133196; Mitogen activated protein kinase kinase kinase 13; Mitogen-activated protein kinase kinase kinase 13; Mixed lineage kinase; MLK; OTTHUMP00000210397] |
Gene, Accession # | [MAP3K13], Gene ID: 9175, NCBI: NP_001229243.1, UniProt: O43283 |
Catalog # | MBS9600260 |
Price | $240, $280 |
Order / More Info | M3K13 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |