GRK (PAN) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRK (PAN)
Clone[S145-20]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatAPC-Cy7 conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionDetects 70 kDa. Cross-reacts with GRK6. G protein-coupled receptor kinases (GRK) are serine/threonine kinases that phosphorylate a variety of G-protein-coupled receptors (GPCRs), specifically activated forms, including adrenergic receptors, muscarinic acetylcholine receptors, dopamine receptors and opioid receptors. GRK receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
ImmunogenImmunogen: Fusion protein amino acids 381-590 (C-terminus) of mouse GRK5. 91% identical to human, and 99% identical to rat. >55% identity with GRK6 and GRK4. >40% identity with GRK7 and RK.
Other Names[Mouse Mouse GRK (pan) IgG1; GRK (pan) : APC/Cy7; G protein-coupled receptor kinase; Pan-GRK; GRK-pan; GRK;]
Gene, Accession #[GRK], Gene ID: 14773, NCBI: NP_061357.3, UniProt: Q8VEB1
Catalog #MBS8003388
Price$510
Order / More InfoGRK (PAN) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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