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Antigenic Specificity | PUF60 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 533 of Human PUF60 |
Other Names | [FIR; PUF60; RoBPI] |
Gene, Accession # | [PUF60], Gene ID: 22827, NCBI: NP_055096 |
Catalog # | MBS9402380 |
Price | $320 |
Order / More Info | PUF60 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |