LDLR (Center), 391-419 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LDLR (Center), 391-419 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: Xenopus, hamster, porcine, rabbit, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human LDLR. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. |
| Immunogen | n/a |
| Other Names | [Low-density lipoprotein receptor; LDL receptor; LDLR] |
| Gene, Accession # | [LDLR], Gene ID: 3949, NCBI: NP_000518.1, UniProt: P01130 |
| Catalog # | MBS9202946 |
| Price | $165, $370 |
| Order / More Info | LDLR (Center), 391-419 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hobbs,H.H., et.al., Hum. Mutat. 1 (6), 445-466 (1992) Brown,M.S. et.al., Proc. Natl. Acad. Sci. U.S.A. 76 (7), 3330-3337 (1979) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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