DFF40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDFF40
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionDFF40 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD (for caspase activated deoxyribonuclease). The human homologue of mouse CAD was more recently identified by three groups independently and termed CPAN, DFF40, and human CAD, respectively. DFF45/ICAD is the inhibitory protein of DFF40/CAD and forms complex with DFF40/CAD. Upon cleavage of DFF45/ICAD by activated caspase, DFF4
ImmunogenImmunogen: DFF40 antibody was raised against a peptide corresponding to amino acids near the center of murine CAD. The sequence differs from human DFF40 by two amino acids. Buffer: DFF40 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[DFF40; CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik; Cad; DNA fragmentation factor subunit beta; Caspase-activated deoxyribonuclease; CAD; DNA fragmentation factor, beta subunit], [Dffb; Dffb; CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik; Cad; CAD; Caspase-activated DNase; DFF-40]
Gene, Accession #[Dffb], Gene ID: 13368, NCBI: NP_031885, UniProt: O54788
Catalog #MBS150514
Price$375
Order / More InfoDFF40 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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