Junin mammarenavirus Nucleoprotein Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Junin mammarenavirus Nucleoprotein |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | Junin mammarenavirus |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation ( |
| Immunogen | Immunogen: Recombinant Junin mammarenavirus Nucleoprotein protein (1-564AA) |
| Other Names | [Nucleoprotein; Nucleocapsid protein; Protein N; N] |
| Gene, Accession # | [N], UniProt: P14239 |
| Catalog # | MBS7049807 |
| Price | $160, $235 |
| Order / More Info | Junin mammarenavirus Nucleoprotein Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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