Edit |   |
Antigenic Specificity | RNA polymerase II CTD repeat YSPTSPS (phospho S) [4H8] - ChIP Grade |
Clone | [4H8] |
Host Species | Mouse |
Reactive Species | mouse, human, Saccharomyces cerevisiae, Arabidopsis thaliana, Caenorhabditis elegans, Fruit fly (Drosophila melanogaster), Schizosaccharomyces pombe, African Green monkey |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.05 mL |
Concentration | 0.8mg/ml |
Applications | Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), ChIP, ChIP/Chip, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognises the C-terminal repeat of the largest subunit of RNA polymerase II. It recognises both unphosphorylated and phosphorylated forms. |
Immunogen | Immunogen: Synthetic peptide: YSPTSpPS (Human). The sequence is repeated multiple times in the C-terminal domain of RNA polymerase II |
Other Names | [DNA directed RNA polymerase II A; DNA-directed RNA polymerase II largest subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; Polr2a; RNA pol II CTD; RNApolymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RPB1; RPB1_HUMAN], [CPL1; CPL1; ATCPL1; ATCPL2; C-terminal domain phosphatase-like 1; C-TERMINAL DOMAIN PHOSPHATASE-LIKE 1; CPL1; F17L22.130; F17L22_130; FIERY 2; FRY2; FRY2; JOE1; FCP-like 1; AtCPL1; CTD phosphatase-like 1] |
Gene, Accession # | Gene ID: 828254, NCBI: Q5YDB6.1, UniProt: Q5YDB6 |
Catalog # | MBS375132 |
Price | $370 |
Order / More Info | RNA polymerase II CTD repeat YSPTSPS (phospho S) [4H8] - ChIP Grade Antibody from MYBIOSOURCE INC. |
Product Specific References | The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase Yart A et al. Cell Biol. 2005 Jun;25(12):5052-60 ChIP ; HumanPMID: 15923622 Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation Kristjuhan A, Wittschieben BO, Walker J, Roberts D, Cairns BR, Svejstrup JQ. (Proc Natl Acad Sci U S A,2003) PUBMED Keren-Shaul H et al. Pre-mRNA splicing is a determinant of nucleosome organization. PLoS One 8:e53506 (2013). WB, ChIP ; Human PUBMED Schmucker AC et al. Distal Interleukin-1beta (IL-1beta) Response Element of Human Matrix Metalloproteinase-13 (MMP-13) Binds Activator Protein 1 (AP-1) Transcription Factors and Regulates Gene Expression. J Biol Chem 287:1189-97 (2012). ChIP ; Human PUBMED Davidson L et al. Co-transcriptional degradation of aberrant pre-mRNA by Xrn2. EMBO J 31:2566-78 (2012). ChIP PUBMED Harrigan JA et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J Cell Biol 193:97-108 (2011). ICC/IF ; Human PUBMED Chen X et al. Sequential changes at differentiation gene promoters as they become active in a stem cell lineage. Development 138:2441-50 (2011) PUBMED |